Jennifer Saunders, Jo Brand, Jason Manford, Paul O’Grady, Frank Skinner and Claudia Winkleman will judge the acts each week.
Both the home audience and judges will have a say on who goes through to the live finale, but it will be the viewers at home who choose their winner.
The announcement also included the songs that the stars will be tackling.
Famous Astrologer, Russell Grant, will channel his inner-diva when he performs Diana Ross’s ‘Chain Reaction’.
Some of the stars of Let’s Sing and Dance for Comic Relief
Some of the judges on Let’s Dance for Comic Relief
Russell Grant will perform a Diana Ross hit
Also taking on an old classic will be Sally Lindsay who is due to perform Slade’s ‘Cum On Feel the Noize’.
Harriet Thorpe and Helen Lederer will don their sequins and platforms to perform an Absolutely Fabulous rendition of ABBA’s ‘Dancing Queen’.
But they’re not all performing old classics with the stars of Casualty and Holby City joining forces to perform ‘Uptown Funk’.
Meanwhile Sara Pascoe will act out Sia’s ‘Chandelier’.
Ab Fab stars, Helen Lederer and Harriet Thorpe will do their best ABBA impression
The One Show will be performing a top secret routine
Stars from The One Show, including Angellica Bell and Iwan Thomas, are keeping their group performance a secret.
The BBC has also announced a French and Saunders reunion as well as the unlikely combination of Katie Price and Stephen Hawking.
The Red Nose Day telethon will air across the BBC on March 24.